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NFL odds and matchups, Week 4, 2025

Show 16 games already played
Thu, Sep 25, 8:15 PM ETFinalDivision game· State Farm Stadium
IndoorsRest SEA 4d · ARI 4dQB SEA Sam Darnold · ARI Kyler Murray

Closing · Spread SEA -1.5 · Total 43.5 · ML -125 / +105

Matchup
Sun, Sep 28, 9:30 AM ETFinal· Acrisure Stadium
61°Rest MIN 7d · PIT 7dQB MIN Carson Wentz · PIT Aaron Rodgers

Closing · Spread MIN -2.5 · Total 41.5 · ML -148 / +124

Matchup
Sun, Sep 28, 1:00 PM ETFinal· Mercedes-Benz Stadium
IndoorsRest WSH 7d · ATL 7dQB WSH Jayden Daniels · ATL Michael Penix

Closing · Spread ATL -2.5 · Total 43.5 · ML +120 / -142

Matchup
Sun, Sep 28, 1:00 PM ETFinal· New Era Field
73°Rest NO 7d · BUF 10dQB NO Spencer Rattler · BUF Josh Allen

Closing · Spread BUF -15.5 · Total 48.5 · ML +800 / -1350

Matchup
Sun, Sep 28, 1:00 PM ETFinal· Ford Field
IndoorsRest CLE 7d · DET 6dQB CLE Joe Flacco · DET Jared Goff

Closing · Spread DET -10 · Total 44.5 · ML +410 / -550

Matchup
Sun, Sep 28, 1:00 PM ETFinalDivision game· NRG Stadium
IndoorsRest TEN 7d · HOU 7dQB TEN Cam Ward · HOU C.J. Stroud

Closing · Spread HOU -7.5 · Total 39.5 · ML +340 / -440

Matchup
Sun, Sep 28, 1:00 PM ETFinal· Gillette Stadium
76°Rest CAR 7d · NE 7dQB CAR Bryce Young · NE Drake Maye

Closing · Spread NE -5.5 · Total 42.5 · ML +215 / -265

Matchup
Sun, Sep 28, 1:00 PM ETFinal· MetLife Stadium
81°Rest LAC 7d · NYG 7dQB LAC Justin Herbert · NYG Jaxson Dart

Closing · Spread LAC -6 · Total 43.5 · ML -285 / +230

Matchup
Sun, Sep 28, 1:00 PM ETFinal· Raymond James Stadium
88°Rest PHI 7d · TB 7dQB PHI Jalen Hurts · TB Baker Mayfield

Closing · Spread PHI -3.5 · Total 44.5 · ML -185 / +154

Matchup
Sun, Sep 28, 4:05 PM ETFinal· SoFi Stadium
IndoorsRest IND 7d · LAR 7dQB IND Daniel Jones · LAR Matthew Stafford

Closing · Spread LAR -3.5 · Total 49.5 · ML +154 / -185

Matchup
Sun, Sep 28, 4:05 PM ETFinal· Levi's Stadium
72°Rest JAX 7d · SF 7dQB JAX Trevor Lawrence · SF Brock Purdy

Closing · Spread SF -3.5 · Total 45.5 · ML +150 / -180

Matchup
Sun, Sep 28, 4:25 PM ETFinal· GEHA Field at Arrowhead Stadium
89° · 10 mph windRest BAL 6d · KC 7dQB BAL Lamar Jackson · KC Patrick Mahomes

Closing · Spread BAL -2.5 · Total 48.5 · ML -148 / +124

Matchup
Sun, Sep 28, 4:25 PM ETFinal· Allegiant Stadium
IndoorsRest CHI 7d · LV 7dQB CHI Caleb Williams · LV Geno Smith

Closing · Spread LV -1.5 · Total 47.5 · ML +105 / -125

Matchup
Sun, Sep 28, 8:20 PM ETFinal· AT&T Stadium
IndoorsRest GB 7d · DAL 7dQB GB Jordan Love · DAL Dak Prescott

Closing · Spread GB -7 · Total 47.5 · ML -345 / +275

Matchup
Mon, Sep 29, 7:15 PM ETFinalDivision game· Hard Rock Stadium
88° · 17 mph windRest NYJ 8d · MIA 11dQB NYJ Justin Fields · MIA Tua Tagovailoa

Closing · Spread MIA -2.5 · Total 44.5 · ML +124 / -148

Matchup
Mon, Sep 29, 8:15 PM ETFinal· Empower Field at Mile High
66° · 12 mph windRest CIN 8d · DEN 8dQB CIN Jake Browning · DEN Bo Nix

Closing · Spread DEN -7.5 · Total 44.5 · ML +360 / -470

Matchup
About this page

Kickoffs, lines and conditions for every game. 16 of 16 final.

Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.