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NFL odds and matchups, Week 10, 2025

Show 14 games already played
Thu, Nov 6, 8:15 PM ETFinalDivision game· Empower Field at Mile High
60° · 10 mph windRest LV 4d · DEN 4dQB LV Geno Smith · DEN Bo Nix

Closing · Spread DEN -9.5 · Total 42.5 · ML +380 / -500

Matchup
Sun, Nov 9, 9:30 AM ETFinal· Lucas Oil Stadium
IndoorsRest ATL 7d · IND 7dQB ATL Michael Penix · IND Daniel Jones

Closing · Spread IND -6.5 · Total 48.5 · ML +250 / -310

Matchup
Sun, Nov 9, 1:00 PM ETFinalDivision game· Bank of America Stadium
73° · 15 mph windRest NO 7d · CAR 7dQB NO Tyler Shough · CAR Bryce Young

Closing · Spread CAR -5.5 · Total 38.5 · ML +200 / -245

Matchup
Sun, Nov 9, 1:00 PM ETFinal· Soldier Field
33° · 10 mph windRest NYG 7d · CHI 7dQB NYG Jaxson Dart · CHI Caleb Williams

Closing · Spread CHI -4.5 · Total 45.5 · ML +180 / -218

Matchup
Sun, Nov 9, 1:00 PM ETFinalDivision game· NRG Stadium
IndoorsRest JAX 7d · HOU 7dQB JAX Trevor Lawrence · HOU Davis Mills

Closing · Spread JAX -1.5 · Total 37.5 · ML -115 / -105

Matchup
Sun, Nov 9, 1:00 PM ETFinalDivision game· Hard Rock Stadium
84°Rest BUF 7d · MIA 10dQB BUF Josh Allen · MIA Tua Tagovailoa

Closing · Spread BUF -8.5 · Total 50.5 · ML -455 / +350

Matchup
Sun, Nov 9, 1:00 PM ETFinal· U.S. Bank Stadium
IndoorsRest BAL 10d · MIN 7dQB BAL Lamar Jackson · MIN J.J. McCarthy

Closing · Spread BAL -4.5 · Total 48.5 · ML -230 / +190

Matchup
Sun, Nov 9, 1:00 PM ETFinal· MetLife Stadium
62° · 12 mph windRest CLE 14d · NYJ 14dQB CLE Dillon Gabriel · NYJ Tyrod Taylor

Closing · Spread CLE -1.5 · Total 37.5 · ML -130 / +110

Matchup
Sun, Nov 9, 1:00 PM ETFinal· Raymond James Stadium
82° · 11 mph windRest NE 7d · TB 14dQB NE Drake Maye · TB Baker Mayfield

Closing · Spread TB -2.5 · Total 48.5 · ML +124 / -148

Matchup
Sun, Nov 9, 4:05 PM ETFinalDivision game· Lumen Field
59°Rest ARI 6d · SEA 7dQB ARI Jacoby Brissett · SEA Sam Darnold

Closing · Spread SEA -7 · Total 44.5 · ML +270 / -340

Matchup
Sun, Nov 9, 4:25 PM ETFinalDivision game· Levi's Stadium
77°Rest LAR 7d · SF 7dQB LAR Matthew Stafford · SF Mac Jones

Closing · Spread LAR -5.5 · Total 49.5 · ML -258 / +210

Matchup
Sun, Nov 9, 4:25 PM ETFinal· FedExField
64°Rest DET 7d · WSH 7dQB DET Jared Goff · WSH Marcus Mariota

Closing · Spread DET -8.5 · Total 49.5 · ML -455 / +350

Matchup
Sun, Nov 9, 8:20 PM ETFinal· SoFi Stadium
IndoorsRest PIT 7d · LAC 7dQB PIT Aaron Rodgers · LAC Justin Herbert

Closing · Spread LAC -3 · Total 45.5 · ML +136 / -162

Matchup
Mon, Nov 10, 8:15 PM ETFinal· Lambeau Field
33°Rest PHI 15d · GB 8dQB PHI Jalen Hurts · GB Jordan Love

Closing · Spread GB -1.5 · Total 45.5 · ML -110 / -110

Matchup
About this page

Kickoffs, lines and conditions for every game. 14 of 14 final.

Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.