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NFL odds and matchups, Week 5, 2025

Show 14 games already played
Thu, Oct 2, 8:15 PM ETFinalDivision game· SoFi Stadium
IndoorsRest SF 4d · LAR 4dQB SF Mac Jones · LAR Matthew Stafford

Closing · Spread LAR -8.5 · Total 43.5 · ML +340 / -440

Matchup
Sun, Oct 5, 9:30 AM ETFinal· FirstEnergy Stadium
61° · 14 mph windRest MIN 7d · CLE 7dQB MIN Carson Wentz · CLE Dillon Gabriel

Closing · Spread MIN -3.5 · Total 35.5 · ML -198 / +164

Matchup
Sun, Oct 5, 1:00 PM ETFinal· M&T Bank Stadium
78°Rest HOU 7d · BAL 7dQB HOU C.J. Stroud · BAL Cooper Rush

Closing · Spread HOU -2.5 · Total 41.5 · ML -148 / +124

Matchup
Sun, Oct 5, 1:00 PM ETFinal· Bank of America Stadium
77°Rest MIA 6d · CAR 7dQB MIA Tua Tagovailoa · CAR Bryce Young

Closing · Spread MIA -1.5 · Total 44.5 · ML -120 / +100

Matchup
Sun, Oct 5, 1:00 PM ETFinal· Lucas Oil Stadium
IndoorsRest LV 7d · IND 7dQB LV Geno Smith · IND Daniel Jones

Closing · Spread IND -7 · Total 46.5 · ML +285 / -360

Matchup
Sun, Oct 5, 1:00 PM ETFinal· Mercedes-Benz Superdome
IndoorsRest NYG 7d · NO 7dQB NYG Jaxson Dart · NO Spencer Rattler

Closing · Spread NO -1.5 · Total 41.5 · ML +100 / -120

Matchup
Sun, Oct 5, 1:00 PM ETFinal· MetLife Stadium
82°Rest DAL 7d · NYJ 6dQB DAL Dak Prescott · NYJ Justin Fields

Closing · Spread NYJ -1.5 · Total 48.5 · ML -105 / -115

Matchup
Sun, Oct 5, 1:00 PM ETFinal· Lincoln Financial Field
80°Rest DEN 6d · PHI 7dQB DEN Bo Nix · PHI Jalen Hurts

Closing · Spread PHI -3.5 · Total 44.5 · ML +180 / -218

Matchup
Sun, Oct 5, 4:05 PM ETFinal· State Farm Stadium
IndoorsRest TEN 7d · ARI 10dQB TEN Cam Ward · ARI Kyler Murray

Closing · Spread ARI -7.5 · Total 41.5 · ML +330 / -425

Matchup
Sun, Oct 5, 4:05 PM ETFinal· Lumen Field
61°Rest TB 7d · SEA 10dQB TB Baker Mayfield · SEA Sam Darnold

Closing · Spread SEA -3.5 · Total 44.5 · ML +150 / -180

Matchup
Sun, Oct 5, 4:25 PM ETFinal· Paycor Stadium
84°Rest DET 7d · CIN 6dQB DET Jared Goff · CIN Jake Browning

Closing · Spread DET -10.5 · Total 49.5 · ML -575 / +425

Matchup
Sun, Oct 5, 4:25 PM ETFinal· SoFi Stadium
IndoorsRest WSH 7d · LAC 7dQB WSH Jayden Daniels · LAC Justin Herbert

Closing · Spread LAC -2.5 · Total 47.5 · ML +130 / -155

Matchup
Sun, Oct 5, 8:20 PM ETFinalDivision game· New Era Field
66°Rest NE 7d · BUF 7dQB NE Drake Maye · BUF Josh Allen

Closing · Spread BUF -7.5 · Total 49.5 · ML +310 / -395

Matchup
Mon, Oct 6, 8:15 PM ETFinal· TIAA Bank Stadium
80° · 12 mph windRest KC 8d · JAX 8dQB KC Patrick Mahomes · JAX Trevor Lawrence

Closing · Spread KC -3.5 · Total 45.5 · ML -198 / +164

Matchup
About this page

Kickoffs, lines and conditions for every game. 14 of 14 final.

Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.