College Football odds and matchups, Week 6, 2025
Featured games16 games
Ranked matchups and prime-time games (kickoff 7 PM ET or later).
Thursday, Oct 21 game
Closing · Spread SHSU -2.5 · Total 52.5 · ML -130 / +110
MatchupFriday, Oct 31 game
Closing · Spread BYU -19.5 · Total 46.5 · ML +850 / -1450
MatchupSaturday, Oct 414 games
Closing · Spread UGA -19.5 · Total 48.5 · ML +850 / -1450
Matchup
Closing · Spread CIN -1.5 · Total 55.5 · ML +105 / -125
Matchup
Closing · Spread MICH -17.5 · Total 42.5 · ML +550 / -800
Matchup
Closing · Spread ILL -7 · Total 54.5 · ML -310 / +250
Matchup
Closing · Spread PSU -24.5 · Total 48.5 · ML -2400 / +1200
Matchup
Closing · Spread TEX -4.5 · Total 42.5 · ML -205 / +170
Matchup
Closing · Spread ALA -13.5 · Total 57.5 · ML +400 / -535
Matchup
Closing · Spread ND -21.5 · Total 63.5 · ML +900 / -1600
Matchup
Closing · Spread LOU -6.5 · Total 59.5 · ML +205 / -250
Matchup
Closing · Spread OU -46.5 · Total 53.5
Matchup
Closing · Spread TTU -13.5 · Total 51.5 · ML -520 / +390
Matchup
Closing · Spread OSU -23.5 · Total 42.5 · ML +1300 / -2800
Matchup
Closing · Spread MIA -3.5 · Total 54.5 · ML -170 / +142
Matchup
Closing · Spread TA&M -17.5 · Total 57.5 · ML +600 / -900
MatchupAll games35 games
Every other game, in kickoff order.
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About this page
Kickoffs, lines and conditions for every game. 51 of 51 final.
Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.