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College Football odds and matchups, Week 3, 2025

Featured games16 games

Ranked matchups and prime-time games (kickoff 7 PM ET or later).

Saturday, Sep 1316 games

Sat, Sep 13, 12:00 PM ETFinalConference game· Northwestern Medicine Field at Martin Stadium
54°Rest ORE 7d · NU 8dQB ORE Dante Moore · NU Preston Stone

Closing · Spread ORE -25.5 · Total 50.5 · ML -3200 / +1400

Matchup
Sat, Sep 13, 12:00 PM ETFinalConference game· Bobby Dodd Stadium
80°Rest CLEM 7d · GT 7dQB CLEM Cade Klubnik · GT Aaron Philo

Closing · Spread CLEM -3 · Total 51.5 · ML -142 / +120

Matchup
Sat, Sep 13, 12:00 PM ETFinal· Lincoln Financial Field
78°Rest OU 7d · TEM 7dQB OU John Mateer · TEM Evan Simon

Closing · Spread OU -23.5 · Total 50.5 · ML -2400 / +1200

Matchup
Sat, Sep 13, 12:00 PM ETFinal· Bryant-Denny Stadium
86°Rest WIS 7d · ALA 7dQB WIS Danny O'Neil · ALA Ty Simpson

Closing · Spread ALA -17.5 · Total 45.5 · ML +750 / -1200

Matchup
Sat, Sep 13, 3:30 PM ETFinal· Beaver Stadium
74°Rest VILL 7d · PSU 7dQB VILL Connor Watkins · PSU Drew Allar

Closing · Spread PSU -46.5 · Total 57.5

Matchup
Sat, Sep 13, 3:30 PM ETFinalConference game· Neyland Stadium
83°Rest UGA 7d · TENN 7dQB UGA Gunner Stockton · TENN Joey Aguilar

Closing · Spread UGA -3.5 · Total 50.5 · ML -166 / +140

Matchup
Sat, Sep 13, 4:00 PM ETFinal· Centennial Bank Stadium
78°Rest ISU 7d · ARST 7dQB ISU Rocco Becht · ARST Jaylen Raynor

Closing · Spread ISU -21 · Total 55.5 · ML -1450 / +850

Matchup
Sat, Sep 13, 4:15 PM ETFinal· DKR-Texas Memorial Stadium
92°Rest UTEP 7d · TEX 7dQB UTEP Malachi Nelson · TEX Arch Manning

Closing · Spread TEX -39.5 · Total 52.5

Matchup
Sat, Sep 13, 4:30 PM ETFinal· Hard Rock Stadium
76°Rest USF 7d · MIA 7dQB USF Byrum Brown · MIA Carson Beck

Closing · Spread MIA -17.5 · Total 56.5 · ML +550 / -800

Matchup
Sat, Sep 13, 7:00 PM ETFinal· Ohio Stadium
80°Rest OHIO 7d · OSU 7dQB OHIO Parker Navarro · OSU Julian Sayin

Closing · Spread OSU -28.5 · Total 49.5 · ML +1700 / -4500

Matchup
Sat, Sep 13, 7:00 PM ETFinal· Gies Memorial Stadium
86°Rest WMU 7d · ILL 7dQB WMU Broc Lowry · ILL Luke Altmyer

Closing · Spread ILL -27.5 · Total 50.5 · ML +1800 / -5000

Matchup
Sat, Sep 13, 7:00 PM ETFinalConference game· Vaught-Hemingway Stadium
51°Rest ARK 7d · MISS 7d

Closing · Spread MISS -3.5 · Total 60.5 · ML +145 / -175

Matchup
Sat, Sep 13, 7:30 PM ETFinalConference game· Tiger Stadium (LA)
94°Rest FLA 7d · LSU 7dQB FLA D.J. Lagway · LSU Garrett Nussmeier

Closing · Spread LSU -4.5 · Total 47.5 · ML +180 / -218

Matchup
Sat, Sep 13, 7:30 PM ETFinal· Notre Dame Stadium
55°Rest TA&M 7d · ND 13dQB TA&M Marcel Reed · ND C.J. Carr

Closing · Spread ND -6.5 · Total 49.5 · ML +200 / -245

Matchup
Sat, Sep 13, 7:45 PM ETFinalConference game· Williams-Brice Stadium
81°Rest VAN 7d · SC 7dQB VAN Diego Pavia · SC Lanorris Sellers

Closing · Spread SC -3 · Total 48.5 · ML +130 / -155

Matchup
Sat, Sep 13, 8:00 PM ETFinal· War Memorial Stadium
56°Rest UTAH 7d · WYO 7dQB UTAH Devon Dampier · WYO Kaden Anderson

Closing · Spread UTAH -24.5 · Total 47.5 · ML -3200 / +1400

Matchup

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Kickoffs, lines and conditions for every game. 70 of 70 final.

Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.