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College Football odds and matchups, Week 12, 2025

Featured games16 games

Ranked matchups and prime-time games (kickoff 7 PM ET or later).

Friday, Nov 141 game

Fri, Nov 14, 9:00 PM ETFinalConference game· Autzen Stadium
56°Rest MINN 13d · ORE 6dQB MINN Drake Lindsey · ORE Dante Moore

Closing · Spread ORE -26.5 · Total 46.5 · ML +1500 / -3600

Matchup

Saturday, Nov 1515 games

Sat, Nov 15, 12:00 PM ETFinalConference game· Memorial Stadium (Bloomington, IN)
68° · 15 mph windRest WIS 7d · IU 7dQB WIS Carter Smith · IU Fernando Mendoza

Closing · Spread IU -28.5 · Total 43.5 · ML +1700 / -4500

Matchup
Sat, Nov 15, 12:00 PM ETFinalConference game· Kyle Field
75° · 12 mph windRest SC 14d · TA&M 7dQB SC Lanorris Sellers · TA&M Marcel Reed

Closing · Spread TA&M -16.5 · Total 49.5 · ML +600 / -900

Matchup
Sat, Nov 15, 12:00 PM ETFinal· Acrisure Stadium
60°Rest ND 7d · PITT 14dQB ND C.J. Carr · PITT Mason Heintschel

Closing · Spread ND -12.5 · Total 55.5 · ML -485 / +370

Matchup
Sat, Nov 15, 12:00 PM ETFinalConference game· Wrigley Field
64° · 15 mph windRest MICH 14d · NU 8dQB MICH Bryce Underwood · NU Preston Stone

Closing · Spread MICH -10 · Total 41.5 · ML -410 / +320

Matchup
Sat, Nov 15, 3:30 PM ETFinalConference game· Bryant-Denny Stadium
75° · 10 mph windRest OU 14d · ALA 7dQB OU John Mateer · ALA Ty Simpson

Closing · Spread ALA -6.5 · Total 45.5 · ML +205 / -250

Matchup
Sat, Nov 15, 3:30 PM ETFinalConference game· Galaxy Stadium
87° · 11 mph windRest UCF 8d · TTU 7dQB UCF Tayven Jackson · TTU Behren Morton

Closing · Spread TTU -24.5 · Total 48.5 · ML +1300 / -2800

Matchup
Sat, Nov 15, 3:30 PM ETFinalConference game· Alumni Stadium (Chestnut Hill, MA)
45°Rest GT 14d · BC 7dQB GT Haynes King · BC Dylan Lonergan

Closing · Spread GT -16.5 · Total 61.5 · ML -850 / +575

Matchup
Sat, Nov 15, 3:30 PM ETFinalConference game· Los Angeles Memorial Coliseum
58°Rest IOWA 7d · USC 8d

Closing · Spread USC -6.5 · Total 48.5 · ML +190 / -230

Matchup
Sat, Nov 15, 3:35 PM ETFinalConference game· Wallace Wade Stadium
72°Rest UVA 7d · DUKE 7dQB UVA Daniel Kaelin · DUKE Darian Mensah

Closing · Spread DUKE -5.5 · Total 59.5 · ML +180 / -218

Matchup
Sat, Nov 15, 3:40 PM ETFinalConference game· Hard Rock Stadium
78°Rest NCSU 14d · MIA 7dQB NCSU CJ Bailey · MIA Carson Beck

Closing · Spread MIA -16.5 · Total 54.5 · ML +500 / -700

Matchup
Sat, Nov 15, 7:00 PM ETFinalConference game· Vaught-Hemingway Stadium
50°Rest FLA 7d · MISS 7dQB FLA D.J. Lagway · MISS Trinidad Chambliss

Closing · Spread MISS -10.5 · Total 53.5 · ML +340 / -440

Matchup
Sat, Nov 15, 7:00 PM ETFinalConference game· McLane Stadium
78° · 10 mph windRest UTAH 14d · BAY 14dQB UTAH Devon Dampier · BAY Sawyer Robertson

Closing · Spread UTAH -9.5 · Total 60.5 · ML -360 / +285

Matchup
Sat, Nov 15, 7:30 PM ETFinalConference game· Ohio Stadium
62° · 12 mph windRest UCLA 7d · OSU 7d

Closing · Spread OSU -33.5 · Total 46.5 · ML +2000 / -6500

Matchup
Sat, Nov 15, 7:30 PM ETFinalConference game· Sanford Stadium
55°Rest TEX 14d · UGA 7dQB TEX Arch Manning · UGA Gunner Stockton

Closing · Spread UGA -3.5 · Total 50.5 · ML +150 / -180

Matchup
Sat, Nov 15, 10:15 PM ETFinalConference game· LaVell Edwards Stadium
54°Rest TCU 7d · BYU 7dQB TCU Josh Hoover · BYU Bear Bachmeier

Closing · Spread BYU -3 · Total 51.5 · ML +130 / -155

Matchup

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Every other game, in kickoff order.

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Kickoffs, lines and conditions for every game. 59 of 59 final.

Lines are the market's, from the sportsbooks we track; weather is the forecast for kickoff. The model's picks for these games are under Predictions. For information only, not betting advice. 21+ only. Gambling problem? Call or text 1-800-GAMBLER.